Research, biology, and treatments mapped from published papers. Track the progress as new findings come in.
Published papers, case reports, and trial data are systematically reviewed. Every claim traces back to graded evidence — not just answers, but competing hypotheses and open questions.
Molecules, pathways, treatments, and genetic findings linked with evidence grades and source references. Machine-readable JSON-LD schema for every disease.
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Deep, evidence-linked references built from published research.
Rare acquired autoinflammatory disorder characterised by chronic urticarial rash with monoclonal IgM gammopathy and systemic inflammation. First described in 1972 by Liliane Schnitzler, the syndrome involves dysregulated IL-1β signalling driving fever, bone pain, arthralgia, and elevated inflammatory markers.
Chronic rhinosinusitis with nasal polyps (CRSwNP) is a chronic inflammatory disease of the sinonasal mucosa characterised by bilateral polyp growth, persistent nasal obstruction, anosmia, and impaired quality of life. Driven predominantly by type 2 inflammation — with IL-4, IL-5, IL-13, and IgE as key mediators — CRSwNP affects 1–4% of the general population and 20–30% of all chronic rhinosinusitis patients.